Publications

Fowle H, Zhao Z, Xu Q, Wasserman JS, Wang X, Adeyemi M, Feiser F, Kurimchak AN, Atar D, McEwan BC, Kettenbach AN, Page R, Peti W, Dunbrack RL, Graña X. PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein. eLife 10:e63181, 2021.

Truong B, Zhang Y, Fahl S, Cai KQ, Martinez E, Al-Saleem ED, Gong Y, Liebermann D, Soboloff J, Dunbrack R, Levine RL, Kappes DJ, Sykes SM, Shapiro P, Wiest D. ERK2 Substrate Binding Domains Perform Opposing Roles in Pathogenesis of a JAK2V617F-Driven Myeloproliferative Neoplasm. Blood 138:2547, 2021

Kueppers F, Andrake MD, Xu Q, Dunbrack RL Jr, Kim J, Sanders CL. Protein modeling to assess the pathogenicity of rare variants of SERPINA1 in patients suspected of having Alpha 1 Antitrypsin Deficiency. BMC Med Genet.  20:125, 2019. PubMed PMID: 31307431; PMCID: PMC6631921.

Nicolas E, Demidova EV, Iqbal W, Serebriiskii IG, Vlasenkova R, Ghatalia P, Zhou Y, Rainey K, Forman AF, Dunbrack RL Jr, Golemis EA, Hall MJ, Daly MB, Arora S. Interaction of germline variants in a family with a history of early-onset clear cell renal cell carcinoma. Mol Genet Genomic Med. e556, 2019. PMID: 30680959. PMCID: PMC6418363.

Matthew EM, Yang Z, Peri S, Andrake M, Dunbrack R, Ross E, El-Deiry WS. Plk2 Loss Commonly Occurring in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling. Neoplasia. 20:244-255, 2018. PMID: 29448085; PMCID: PMC5849802.

Gupta S, Kelow S, Wang L, Andrake MD, Dunbrack RL Jr, Kruger WD. Mouse modeling and structural analysis of the p.G307S mutation in human cystathionine β-synthase (CBS) reveal effects on CBS activity but not stability. J Biol Chem. 293:13921-13931, 2018.  PubMed PMID: 30030379; PubMed Central PMCID: PMC6130948.

Fahl SP, Coffey F, Kain L, Zarin P, Dunbrack RL Jr., Teyton L, Zúñiga-Pflücker JC, Kappes DJ, Wiest DL. Role of a selecting ligand in shaping the murine γδ-TCR repertoire. Proc Natl Acad Sci U S A. 115:1889-1894, 2018. PMID: 29432160; PMCID: PMC5828614.

Arora S, Huwe PJ, Sikder R, Shah M, Browne AJ, Lesh R, Nicolas E, Deshpande S, Hall MJ, Dunbrack RL Jr, Golemis EA. Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods. Cancer Biol Ther.18:519-533, 2017. PMID: 28494185; PMCID: PMC5639829. 

Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, Upton JW, Balachandran S. DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death. Cell Host Microbe 20:674-681, 2016. PMID: 27746097; PMCID: PMC5687825

Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH. Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas. Gastroenterology. 149:1872-1883.e9, 2015. PMID: 26344056, PMCID: PMC4663158