Understanding How Protein Kinases Activate Themselves Could Spawn New Anticancer Therapies
PHILADELPHIA (December 15, 2015) – Protein kinases play important roles in a range of cellular processes and have been implicated in diverse diseases, from cancer to obesity. Most of these proteins regulate their own activity through a biochemical process called autophosphorylation. Capturing snapshots of this event as it unfolds could be the key to understanding the molecular origins of disease and to developing a new generation of therapies.