Joseph R. Triggs, MD, PhD

Assistant Professor

Specialties

Interventional Gastroenterology ;
Gastroenterology

Areas of Expertise

Colorectal Cancer, Stomach (Gastric) Cancer, GERD & Barrett's Esophagus, Esophageal Cancer

Distinctions

Clinical Locations

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Phone: 888-369-2427

Educational Background

University of Pennsylvania Perelman School of Medicine, Advanced Endoscopy Fellow, 2020
Northwestern University Feinberg School of Medicine, Alvin I. Goodman Esophageal Fellowship, 2019
McGaw Medical Center of Northwestern University, Fellowship in Gastroenterology & Hepatology, 2019
McGaw Medical Center of Northwestern University Internship and Residency in Internal Medicine, 2015
University of Chicago, Pritzker School of Medicine, Chicago, IL Doctorate of Medicine, 2013
University of Pennsylvania, Philadelphia, PA, Bachelor of Arts with Honors Major: Biology Minor: Economics, 2005
University of Chicago Graduate School, Biological Sciences Division, Chicago IL Doctorate of Philosophy in Immunology
Thesis: Genomic analysis of transcriptional and chromatin dynamics during B cell development Advisor: Harinder Singh PhD, 2011

Certifications

American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Gastroenterology

Memberships

The International Society for Diseases of the Esophagus, 2020 – Present
American Neurogastroenterology and Motility Society, 2019 – Present
American Foregut Society, 2019 – Present
American College of Gastroenterology, 2016 – Present
American Gastroenterological Association, 2016 – Present
American Society for Gastrointestinal Endoscop, 2015 – Present
- ASGE DDW Video Plenary and World Cup Committee 2020 to present

Honors & Awards

Philadelphia Magazine Top Doctors, 2024
Physician Scientist Training Program, Northwestern University Feinberg School of Medicine, 2019
Hoffman-Levin Fellowship Award, Northwestern University Feinberg School of Medicine, Salary support for outstanding work in translational medicine, 2016
Northwestern University Department of Medicine, Junior Student Resident Teaching Award, 2015
Richard W. Reilly Award, University of Chicago Pritzker School of Medicine – Outstanding aptitude in the field of Gastroenterology, 2013
University of Pennsylvania, Biology Departmental Honors, 2005

Selected Publications

Halder S, Acharya S, Kou W, Campagna RAJ, Triggs JR, Carlson DA, Aadam AA, Hungness ES, Kahrilas PJ, Pandolfino JE, Patankar NA. Myotomy technique and esophageal contractility impact blown-out myotomy formation in achalasia: an in silico investigation. Am J Physiol Gastrointest Liver Physiol. 2022 May 1;322(5):G500-G512. doi: 10.1152/ajpgi.00281.2021. Epub 2022 Feb 16. PMID: 35170365.

Beveridge CA, Triggs JR, Thanawala SU, Ahuja NK, Falk GW, Benitez AJ, Lynch KL. Can FLIP guide therapy in idiopathic esophagogastric junction outflow obstruction? Dis Esophagus. 2021 Dec 2:doab077. doi: 10.1093/dote/doab077. Epub ahead of print. PMID: 34864928.

Thiruvengadam NR, Saumoy M, Schneider Y, Attala S, Triggs J, Lee P, Kochman ML. A Cost-Effectiveness Analysis for Post-ERCP Pancreatitis Prophylaxis in the United States. Clin Gastroenterol Hepatol. 2021 Sep 2:S1542-3565(21)00930-7. doi: 10.1016/j.cgh.2021.08.050. Epub ahead of print. PMID: 34481952.

Tomizawa Y, Mahmud N, Dasher K, Triggs JR, Saumoy M, Falk GW, Ginsberg GG. Type II achalasia is associated with a comparably favorable outcome following per oral endoscopic myotomy. Dis Esophagus. 2021 Jun 14;34(6):doaa107. doi: 10.1093/dote/doaa107. PMID: 33180122.

Vosoughi K, Ichkhanian Y, Benias P, Miller L, Aadam AA, Triggs JR, Law R, Hasler W, Bowers N, Chaves D, Ponte-Neto AM, Draganov P, Yang D, El Halabi M, Sanaei O, Brewer Gutierrez OI, Bulat RS, Pandolfino J, Khashab M. Gastric per-oral endoscopic myotomy (G-POEM) for refractory gastroparesis: results from an international prospective trial. Gut. 2021 Mar 19:gutjnl-2020-322756. doi: 10.1136/gutjnl-2020-322756. Epub ahead of print. PMID: 33741641.

Campagna RAJ, Cirera A, Holmstrom AL, Triggs JR, Teitelbaum EN, Carlson DA, Pandolfino JE, Hungness ES. Outcomes of 100 Patients More Than 4 Years After POEM for Achalasia. Ann Surg. 2021 Jun 1;273(6):1135-1140. doi: 10.1097/SLA.0000000000004830. PMID: 33914488.

Campbell CH, Triggs JR, Miller FH, Komanduri S. Endoscopic Ultrasound for Evaluation of Pancreatic Duct "Cutoff" Identified on Magnetic Resonance Imaging Improves the Diagnostic Yield of Occult Malignancy. Pancreas. 2021 Apr 1;50(4):e43-e45. doi: 10.1097/MPA.0000000000001789. PMID: 33939682.

Triggs JR, Krause AJ, Carlson DA, Donnan EN, Campagna RAJ, Jain AS, Kahrilas PJ, Hungness ES, Pandolfino JE. Blown-out myotomy: an adverse event of laparoscopic Heller myotomy and peroral endoscopic myotomy for achalasia. Gastrointest Endosc. 2020 Jul 25:S0016-5107(20)34636-8. doi: 10.1016/j.gie.2020.07.041. Epub ahead of print. PMID: 32721488; PMCID: PMC7855725.

Krause AJ, Su H, Triggs JR, Beveridge C, Baumann AJ, Donnan E, Pandolfino JE, Carlson DA. Multiple rapid swallows and rapid drink challenge in patients with esophagogastric junction outflow obstruction on high-resolution manometry. Neurogastroenterol Motil. 2021 Mar;33(3):e14000. doi: 10.1111/nmo.14000. Epub 2020 Oct 11. PMID: 33043557; PMCID: PMC7902305.

Yadlapati R, Masihi M, Gyawali CP, Carlson DA, Kahrilas PJ, Nix BD, Jain A, Triggs JR, Vaezi MF, Kia L, Kaizer A, Pandolfino JE. Ambulatory Reflux Monitoring Guides Proton Pump Inhibitor Discontinuation in Patients With Gastroesophageal Reflux Symptoms: A Clinical Trial. Gastroenterology. 2021 Jan;160(1):174-182.e1. doi: 10.1053/j.gastro.2020.09.013. Epub 2020 Sep 16. PMID: 32949568; PMCID: PMC7755671.

... Expand

Carlson DA, Kou W, Rooney KP, Baumann AJ, Donnan E, Triggs JR, Teitelbaum EN, Holmstrom A, Hungness E, Sethi S, Kahrilas PJ, Pandolfino JE. Achalasia subtypes can be identified with functional luminal imaging probe (FLIP) panometry using a supervised machine learning process. Neurogastroenterol Motil. 2021 Mar;33(3):e13932. doi: 10.1111/nmo.13932. Epub 2020 Jul 1. PMID: 32608147; PMCID: PMC7775338.

Sloan JA, Triggs JR, Pandolfino JE, Dbouk M, Brewer Gutierrez OI, El Zein M, Quader F, Ichkhanian Y, Gyawali CP, Rubenstein JH, Khashab MA. Treatment experience with a novel 30-mm hydrostatic balloon in esophageal dysmotility: a multicenter retrospective analysis. Gastrointest Endosc. 2020 Dec;92(6):1251-1257. doi: 10.1016/j.gie.2020.04.076. Epub 2020 May 15. PMID: 32417296.

Ichkhanian Y, Vosoughi K, Aghaie Meybodi M, Jacques J, Sethi A, Patel AA, Aadam AA, Triggs JR, Bapaye A, Dorwat S, Benias P, Chaves DM, Barret M, Law RJ, Browers N, Pioche M, Draganov PV, Kotzev A, Estremera F, Albeniz E, Ujiki MB, Callahan ZM, Itani MI, Brewer OG, Khashab MA. Comprehensive Analysis of Adverse Events Associated with Gastric Peroral Endoscopic Myotomy: An International Multicenter Study. Surg Endosc. 2020 Apr 23. doi: 10.1007/s00464-020-07570-z. Epub ahead of print. Erratum in: Surg Endosc. 2020 May 18;: PMID: 32328824.

Rooney KP, Baumann AJ, Donnan E, Kou W, Triggs JR, Prescott J, Decorrevont A, Dorian E, Kahrilas PJ, Pandolfino JE, Carlson DA. Esophagogastric Junction Opening Parameters Are Consistently Abnormal in Untreated Achalasia. Clin Gastroenterol Hepatol. 2020 Apr 11:S1542-3565(20)30490-0. doi: 10.1016/j.cgh.2020.03.069. Epub ahead of print. PMID: 32289545; PMCID: PMC7554071.

Baumann AJ, Donnan EN, Triggs JR, Kou W, Prescott J, Decorrevont A, Dorian E, Kahrilas PJ, Pandolfino JE, Carlson DA. Normal Functional Luminal Imaging Probe Panometry Findings Associate With Lack of Major Esophageal Motility Disorder on High-Resolution Manometry. Clin Gastroenterol Hepatol. 2021 Feb;19(2):259-268.e1. doi: 10.1016/j.cgh.2020.03.040. Epub 2020 Mar 20. PMID: 32205217; PMCID: PMC7502471.

Carlson DA, Gyawali CP, Roman S, Vela M, Taft TH, Crowell MD, Ravi K, Triggs JR, Quader F, Prescott J, Lin FTJ, Mion F, Biasutto D, Keefer L, Kahrilas PJ, Pandolfino JE. Esophageal Hypervigilance and Visceral Anxiety Are Contributors to Symptom Severity Among Patients Evaluated With High-Resolution Esophageal Manometry. Am J Gastroenterol. 2020 Mar;115(3):367-375. doi: 10.14309/ajg.0000000000000536. PMID: 31990697; PMCID: PMC7071929.

Triggs JR, Carlson DA, Beveridge C, Kou W, Kahrilas PJ, Pandolfino JE. Functional Luminal Imaging Probe Panometry Identifies Achalasia-Type Esophagogastric Junction Outflow Obstruction. Clin Gastroenterol Hepatol. 2020 Sep;18(10):2209-2217. doi: 10.1016/j.cgh.2019.11.037. Epub 2019 Nov 25. PMID: 31778806; PMCID: PMC7246143.

Vosoughi K, Ichkhanian Y, Jacques J, Aadam AA, Benias PC, Law R, Hasler WL, Canakis A, Ragi O, Triggs J, Bowers N, Brewer Gutierrez OI, Kumbhari V, Kalloo AN, Bulat RS, Pandolfino JE, Khashab MA. Role of endoscopic functional luminal imaging probe in predicting the outcome of gastric peroral endoscopic pyloromyotomy (with video). Gastrointest Endosc. 2020 Jun;91(6):1289-1299. doi: 10.1016/j.gie.2020.01.044. Epub 2020 Feb 6. PMID: 32035074.

Yadlapati R, Triggs J, Quader F, Eluri S, Bhatia S, Kaizer A, Pandolfino JE, Komanduri S, Gyawali P, Shaheen NJ, Menard-Katcher P, Wani S. Reduced Esophageal Contractility Is Associated with Dysplasia Progression in Barrett's Esophagus: A Multicenter Cohort Study. Dig Dis Sci. 2020 Dec;65(12):3631-3638. doi: 10.1007/s10620-020-06098-5. Epub 2020 Feb 5. PMID: 32026276.

Carlson DA, Gyawali CP, Kahrilas PJ, Triggs JR, Falmagne S, Prescott J, Dorian E, Kou W, Lin Z, Pandolfino JE. Esophageal motility classification can be established at the time of endoscopy: a study evaluating real-time functional luminal imaging probe panometry. Gastrointest Endosc. 2019. Epub 2019/07/08. doi: 10.1016/j.gie.2019.06.039. PubMed PMID: 31279625.

Triggs JR, Carlson DA, Beveridge C, Jain A, Tye MY, Kahrilas PJ, Pandolfino JE. Upright Integrated Relaxation Pressure Facilitates Characterization of Esophagogastric Junction Outflow Obstruction. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2019. Epub 2019/02/02. doi: 10.1016/j.cgh.2019.01.024. PubMed PMID: 30708108.

Jain AS, Carlson DA, Triggs JR, Tye M, Kou W, Campagna R, Hungness E, Kim D, Kahrilas PJ, Pandolfino JE. Esophagogastric Junction Distensibility on Functional Lumen Imaging Probe Topography Predicts Treatment Response in Achalasia-Anatomy Matters! Am J Gastroenterol. 2019. Epub 2019/02/12. doi: 10.14309/ajg.0000000000000137. PubMed PMID: 30741739.

Taft TH, Triggs JR, Carlson DA, Guadagnoli L, Tomasino KN, Keefer L, Pandolfino JE. Validation of the oesophageal hypervigilance and anxiety scale for chronic oesophageal disease. Aliment Pharmacol Ther. 2018;47(9):1270-7. Epub 2018/03/13. doi: 10.1111/apt.14605. PubMed PMID: 29528128; PMCID: Pmc5897170.

Taft TH, Carlson DA, Triggs JR, Craft J, Starkey K, Yadlapati R, Gregory D, Pandolfino JE. Evaluating the reliability and construct validity of the Eckardt symptom score as a measure of achalasia severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2018. Epub 2018/01/10. doi: 10.1111/nmo.13287. PubMed PMID: 29315993.

Ochiai K, Maienschein-Cline M, Mandal M, Triggs JR, Bertolino E, Sciammas R, Dinner AR, Clark MR, Singh H. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nature immunology. 2012;13(3):300-7. Epub 2012/01/24. doi: 10.1038/ni.2210. PubMed PMID: 22267219; PMCID: PMC4028049.

Hu S, Zhu X, Triggs JR, Tao Y, Wang Y, Lichtenstein L, Bissonnette M, Musch MW, Chang EB. Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis. American journal of physiology Gastrointestinal and liver physiology. 2009;296(5):G1003-11. Epub 2009/03/21. doi: 10.1152/ajpgi.00027.2009. PubMed PMID: 19299581; PMCID: PMC2696214.

Triggs JR, Falk GW. Best Practices in Surveillance for Barrett's Esophagus. Gastrointest Endosc Clin N Am. 2021 Jan;31(1):59-75. doi: 10.1016/j.giec.2020.08.003. Epub 2020 Oct 21. PMID: 33213800; PMCID: PMC7684982.

Triggs JR, Kahrilas PJ. Editorial: gastric bypass for GERD in class II & III obesity-still the best option? Aliment Pharmacol Ther. 2019;49(12):1535-6. Epub 2019/05/28. doi: 10.1111/apt.15295. PubMed PMID: 31134654.

Triggs JR, Pandolfino J. Recent advances in dysphagia management. F1000Research. 2019;8. Epub 2019/09/12. doi: 10.12688/f1000research.18900.1. PubMed PMID: 31508201; PMCID: PMC6719674.

Triggs JR, Kahrilas PJ. Editorial: symptom association probability during reflux testing-what is the gain? Aliment Pharmacol Ther. 2018;47(9):1317-8. Epub 2018/04/13. doi: 10.1111/apt.14583. PubMed PMID: 29644741.

Triggs JR, Kahrilas PJ. Editorial: Assessing Esophageal Function in Achalasia: The Old and the New. The American Journal Of Gastroenterology. 2018;113:213. doi: 10.1038/ajg.2017.445.

Triggs JR, Pandolfino JE. Book Chapter. Esophageal Strictures. Encyclopedia of Gastroenterology, 2nd edition, 2019. Publication in press.

Triggs JR, Pandolfino JE. Book Chapter. POEM: pre-procedural work-up and indications. Gastrointestinal Interventional Endoscopy: Advanced Techniques, 2018. Publication in press.

Triggs JR, Pandolfino JE. Book Chapter. Esophageal Manometry. Handbook of Gastroenterologic Procedure, 5e, 2018. Publication in press. Collapse

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