Christopher William Schultz, PhD

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Educational Background

PostDoc, National Cancer Institute, 2025

PhD, Genetics, Genomics and Biology of Cancer, Thomas Jefferson University, 2020

BS, Chemistry, Drexel University 2015

Memberships

AACR Membership

Honors & Awards

K99/R00 2023-Present

FARE travel award NIH – competitive travel award 2022

NCI Graduate Student Recruitment Program – Competitive program recruiting graduate students to become fellows at the NCI 2019

Lab Overview

The Schultz lab aims to further understand small cell lung cancer and unique vulnerabilities associated with neuroendocrine differentiation and characteristic mutations present in small cell lung cancer. All work at the Schultz lab is designed to be translationally relevant, with every project aimed at near-term translatability to the clinic if successful.

Selected Publications

https://orcid.org/0000-0001-5731-2847

Additional Publications

1)Schultz CW et al ATR inhibition augments the efficacy of lurbinectedin in small cell lung cancer, PMID:37491889, 2023, EMBO Molecular Medicine 

2)Lorinc S Pongor, Schultz CW et al… Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes, PMID: 36715552, 2023, Cancer Discovery 

3) Schultz CW et al The FDA approved anthelmintic Pyrvinium Pamoate inhibits pancreatic adenocarcinoma through inhibiting HuR and mitochondrial survival pathways, PMID: 34413127, 2021, Molecular Cancer Therapeutics

Open Positions

The Schultz Laboratory at the Temple LKSOM is hiring highly ambitious and self-motivated Postdoctoral Fellows interested in exploring novel therapeutic vulnerabilities for small cell lung cancer (SCLC). The laboratory uses state-of-the-art technologies and collaborations with leading scientist and clinicians to address the following areas: (1) targeting deregulation of G1/S transition for the treatment of SCLC (2) utilizing novel agents to augment standard of care agents for SCLC (3) targeting/further understanding the role of neuroendocrine differentiation and LMNA in SCLC metastasis.

The Schultz laboratory seeks candidates that published peer reviewed manuscripts and that have strong expertise in molecular biology, cancer biology and/or biochemistry. The Schultz lab is committed to helping trainees achieve their own goals on their path towards independence.

ABOUT THE TRAINING ENVIRONMENT

As one of the four original cancer centers to receive comprehensive designation from the National Cancer Institute, Temple LKSOM and their partnership with Fox Chase Cancer Center have been at the forefront of cancer research for almost 90 years. We are home to excellent research facilities, top clinicians and scientists, and outstanding patient care. Our singular focus on cancer, which couples discovery science with state of the art clinical care and population health, remains the foundation of our work. The scientist training programs at Fox Chase Cancer Center provide professional development opportunities in four core areas identified as crucial for successful careers in science, research, and health care including communication, leadership, teaching, and mentorship. Upon joining the program, graduate students and postdocs develop individual development plans to help guide their growth. Training throughout the year is supplemented with free professional development opportunities, including a robust ‘How To’ series, writing courses, networking, mentorship, and teaching opportunities, a trainee-led seminar series, a trainee-led annual Research Conference, and more. Postdocs at Fox Chase Cancer Center are supported by the Temple University Postdoc Association and the Office of Academic Affairs at Fox Chase, and are compensated with competitive pay and benefits.

In addition to the robust training program, scientists at Fox Chase Cancer Center benefit from being part of the rich scientific and biotech environment in the Philadelphia region. Many of our former trainees are now employees (and contacts) at nearby institutions and companies, including The Wistar Institute, Merck, GSK, AACR, and numerous others.

TO APPLY

Email a CV, cover letter that states research interest(s) and goals, and the name of at least three references to [email protected]. Qualified candidates will then be invited to complete a job application.

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