Inflammatory Bowel Disease and Colorectal Cancer Risk: Understanding the Link

• Worldwide, about 7 million people live with inflammatory bowel disease (IBD), a term for chronic inflammation of the gastrointestinal tract. Unfortunately, having one of the two most common inflammatory bowel diseases (Crohn’s disease or ulcerative colitis) can significantly increase one’s colorectal cancer risk. 

  Both conditions involve increased inflammation in the colon, which can lead to the formation of abnormal cells in the colon lining or rectum that can become cancerous. Having very severe inflammation, IBD for more than eight years, a family history of colorectal cancer, or primary sclerosing cholangitis (an inflammatory bile duct condition that affects some people with IBD) can raise that risk even more.

  That’s why it’s crucial for people with IBD to know their risk for colorectal cancer—and what they can do about it.

  Screenings are essential

  When it comes to colorectal cancer, early detection is key. Your doctor can offer individualized advice on the best screening schedule for you. In general, if you’ve had IBD for eight or more years, it is recommended that you undergo a colonoscopy every one to two years.

  IBD patients should also consider an advanced method of cancer screening called chromoendoscopy as part of their colonoscopy. The procedure, which involves spraying blue dye into the colon, can reveal lesions that conventional colonoscopies can’t always detect.

  Other protective measures

  Taking steps to keep your IBD well managed can also go a long way. Seeing your gastroenterologist at least once a year, taking your medications regularly (even when you’re feeling well), and letting your doctor know of any new symptoms (or if someone in your family is diagnosed with colorectal cancer) is incredibly important. Making an effort to eat well, limit red meat consumption, and exercise regularly is also advised.

  Staying aware of your cancer risk on top of dealing with IBD can feel overwhelming, but there’s reason to stay positive. Advancements in colonoscopy technologies are helping to detect signs of cancer earlier, when they’re easier to treat. And thanks to increased screening and inflammation-reducing IBD drugs, fewer people with IBD are developing colorectal cancer today than in the past.

  High-quality care

  At Fox Chase Cancer Center, your colonoscopy will be performed by a gastroenterologist experienced in detecting the early signs of colorectal cancer. And we offer a broad array of endoscopic techniques to ensure you get the high-quality screening you need. 

  To schedule your screening, call 888-369-2427 or request an appointment online.