Fox Chase Cancer Center News

Study Suggests Disrupting DNA Repair Signaling Could Block Cancer Growth

PHILADELPHIA (March 25, 2020)—A study by researchers at Fox Chase Cancer Center published today found that the RNF168 signaling pathway is critical for preventing the growth of BRCA1 mutant cancers, and that new drugs, designed to restore this pathway, could be effective for treating cancers with BRCA1 gene mutations.

VIEW STORY

New Influenza Findings Could Have Key Impact on Cancer Therapies

PHILADELPHIA (March 19, 2020) – Researchers at the Fox Chase Cancer Center have clarified a fundamental host defense mechanism that detects the presence of influenza virus and rapidly destroys infected cells. “Influenza virus Z-RNAs induce ZBP1-mediated necroptosis” was published in Cell.

VIEW STORY