Systemic Therapy for Melanoma

The medical oncologists at Fox Chase Cancer Center are regional and national leaders in the treatment of skin cancer. As part of the multidisciplinary team, your medical oncologist will help to determine your personalized treatment plan, which may include systemic therapies, such as targeted therapy, immunotherapy, or chemotherapy, either as standard of care or as part of a clinical trial.

Isolated Limb Infusion

Metastatic melanoma (cancer that has spread to other parts of the body) is one of the hardest cancers to treat. Isolated Limb Infusion (ILI) is a minimally-invasive procedure for delivering high doses of chemotherapy directly to an arm or leg in people who have a type of metastatic melanoma called in-transit melanoma. By temporarily stopping blood flow to the affected limb, this technique allows the chemotherapy to concentrate where it is needed. Fox Chase in Philadelphia is one of the few cancer centers in the United States with the specialized skills needed to perform ILI. More than 60% of patients respond well to this treatment.