Fox Chase Researchers Find That Astrocytes Generated by Tumor Cells Contribute to SHH-Driven Medulloblastoma Relapse
PHILADELPHIA (July 13, 2021)—Researchers at Fox Chase Cancer Center have recently shown that sonic hedgehog-driven (SHH) medulloblastoma relapse may be prevented by targeting the transdifferentiation—a cell’s ability to convert from one type of cell to another—of astrocytes.