Fox Chase Cancer Center News

PHILADELPHIA (February 25, 2022)—In a study published in the prestigious journal Clinical Cancer Research, Fox Chase Cancer Center researchers show that specific categories of TP53 gene mutations are more likely to associate with CDKN2A gene mutations or high tumor mutation burden in some cases of head and neck cancer.

PHILADELPHIA (February 24, 2022)—Extraskeletal myxoid chondrosarcoma is a rare soft-tissue cancer that can be misdiagnosed. Now researchers at Fox Chase Cancer Center have identified a fusion gene that can help pathologists positively identify these tumors.

PHILADELPHIA (February 24, 2022)—John Karanicolas, PhD, co-leader of the Molecular Therapeutics research program at Fox Chase Cancer Center, has been awarded a $200,000 grant as part of the University City Science Center’s QED Proof-of-Concept Program. The grant will fund research into developing antibodies that could be activated selectively in a tumor by a small molecule.

PHILADELPHIA (February 23, 2022)—On Wednesday, March 2, Fox Chase Cancer Center will host its second annual Cancer Epigenetics Institute Symposium, “From Genes to Chromatin to Therapeutics.” This year’s all-day event will take place at The Franklin Institute in Philadelphia and will include a virtual option for those who cannot attend in person.

PHILADELPHIA (February 17, 2022)—Jonathan Chernoff, MD, PhD, Cancer Center Director at Fox Chase Cancer Center, was recently awarded a $50,000 grant from the Pennsylvania Breast Cancer Coalition.

PHILADELPHIA (February 17, 2022)—Researchers at Fox Chase Cancer Center have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human embryonic stem cells (hESCs) for a process essential to human development.

PHILADELPHIA (February 15, 2022)—Efrat Dotan, MD, chief of the Division of Gastrointestinal Medical Oncology at Fox Chase Cancer Center, has been appointed the vice chair of the National Cancer Institute’s (NCI) Pancreas Task Force as part of the Gastrointestinal Steering Committee (GISC).

PHILADELPHIA (February 14, 2022)—Data from researchers at Fox Chase Cancer Center indicates that advanced kidney cancer patients treated with a combination of nivolumab and axitinib experienced similar therapeutic benefits to those patients treated with other drug combinations with similar safety profiles. The new research was presented at the 2022 ASCO Genitourinary Cancers Symposium in San Francisco, which is being held February 17-19.