Fox Chase Cancer Center News

Biomechanics of Phenylalanine Maintenance Illustrated in New Study

PHILADELPHIA (February 13, 2019) — Fox Chase Cancer Center researchers have published a groundbreaking study that describes for the first time the mechanisms of how the amount of amino acid phenylalanine (Phe) is controlled in blood. Accumulation of Phe can cause phenylketonuria (PKU), a rare genetic condition that can result in permanent neurological damage as well as behavioral abnormalities if not properly managed.

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