Fox Chase Researchers Uncover Achilles' Heel in Aggressive Breast Tumors
PHILADELPHIA (October 12, 2010) – In an unexpected twist, Fox Chase Cancer Center researchers find that the loss of a single protein, Nedd9, initially slows cancer formation but then makes the tumors that do arise more aggressive. The good news, though, is that the lack of Nedd9 also makes the aggressive tumors more sensitive to a class of drugs that are already used in the clinic.